50,000 people either died or relocated when the nuclear reactor Juicebox mentioned overloaded and melted down. It was the worst nuclear disaster in Russia's history. It'll be another 50 years before people can return without radiation suits, and another 100 years before it'll be habitable again
Hashima Island is the king for that. Get this, you can only stay there for a certain number of months, or else you're trapped on the island due to weather patterns.